Incidences of Acute Lymphoblastic Leukemia as per Age: A two year Study

acute hepatitis as a manifestation of acute lymphoblastic leukemia

Primary Malignant Melanoma of the Eye in a 17-Year-Old Girl with Acute Lymphoblastic Leukemia

Herein we describe a case of intraocular melanoma in a17-year old leukemic patient.  The history, histological findings of the enucleated eye, blood and bone marrow of the patient were investigated. The enucleated eye contained epitheloid cell type melanoma instead of leukemic cell infiltration.  We conclude that intraocular malignant melanoma can occur in acute lymphoblastic leukemia.

UBE2Q1, as Down Regulated Gene in Pediatric Acute Lymphoblastic Leukemia

Ubiquitin - proteasome system (UPS), the major protein degradation pathway in the cells, typically degrades short - lived and damaged proteins and regulates growth and stress responses. This pathway is altered in various cancers, including Acute Lymphoblastic Leukemia (ALL). ALL begins with a change in bone marrow cells and is the most common type of leukemia in children under 15 years. UBE2Q1...

Metronomic Effect as A New Hypothesis in Maintenance Therapy of Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia: age and biology

Acute lymphoblastic leukemia (ALL) is the most frequent neoplasm in children, while being relatively rare in adults. The outcome of children with ALL is far superior than that observed in adults, whose survival rates generally do not exceed 40%. A retrospective analysis recently carried out on a large series of cases enrolled in the AIEOP and GIMEMA protocols for the treatment of pediatric and ...